Great Famine may refer to:
China
Great Chinese Famine (1958–1961)
Greece
Great Famine (Greece) (1941–1944)
India
Great Bengal famine of 1770
Great Rajputana Famine (1869) Great Famine of 1876–1878
Ireland
Great Famine (Ireland) (1845–1852), occasion for the great exodus of Irish and the Irish diaspora
Japan
Kan'ei Great Famine (1640–1643) Great Tenmei famine (1782–1788) Tenpō famine or Great Tenpō famine (1833–1837)
Lebanon
Great Famine of Mount Lebanon (1915–1918)
North Korea
North Korean famine (1994–1998)