Chlorpromazine includes the following list of adverse effects (serious adverse effects appear in bold):

Very common

Sedation (cf. "Thorazine shuffle" – a shuffling gait due to sedation) Somnolence Extrapyramidal symptoms Weight gain Orthostatic hypotension Dry mouth Constipation

List of adverse effects of chlorpromazine

Common

ECG changes

Contact dermatitis

Sensitivity to light

Urticaria (hives) Maculopapular rash Petechia or edema Hyperprolactinaemia Impaired thermoregulation Hyperglycaemia Other hypothalamic abnormalities Blurred vision Confusion Raised ANA titre Positive SLE cells Mydriasis Atonic colon Seizure Psychomotor agitation|Agitation (restlessness) Pain at the injection site Injection site abscess

List of adverse effects of chlorpromazine

Uncommon

Miosis

Urinary retention

Nasal congestion

Nausea

Obstipation

Arrhythmias

Skin pigmentation

Glycosuria

Hypoglycaemia

Paralytic ileus

Rare

Agranulocytosis

Haemolytic anaemia

Aplastic anaemia

A-V block

Hypertensive crises

Thrombocytopenic purpura

Exfoliative dermatitis

Toxic epidermal necrolysis

Systemic lupus erythematosus

Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) Water retention Cholestatic jaundice Liver injury Neuroleptic malignant syndrome Myasthenia gravis

List of adverse effects of chlorpromazine

Unknown frequency

Leucopaenia

Eosinophilia

Pancytopaenia

Priapism

Photophobia

Corneal deposits

Respiratory depression

Ventricular tachycardia

QT interval prolongation

Atrial fibrilation

Hyperthermia

Hypothermia

Galactorrhoea

Breast enlargement in either sex

False-positive pregnancy tests

Allergic reaction

Fits

Cerebral oedema

Urinary incontinence

Coagulation defects

Nightmares

Abnormality of cerebrospinal fluid proteins

Dysphoria

Catatonic excitement

Narrow angle glaucoma

Optic atrophy

Pigmentary retinopathy

Amenorrhoea

Infertility

Tardive dyskinesia

Notes

References

Chlorpromazine