The 1926 United States Senate special election in Missouri took place on November 2, 1926 in Missouri. The Republican Senator elected in 1920, Selden P. Spencer, died on May 16, 1925. George Howard Williams was appointed to continue Spencer's term on May 25, and ran in this special election to complete the term. He was defeated by the Democratic nominee Harry B. Hawes, who won 52% of the vote. Hawes also defeated Williams in the regular election held the same day.
Democratic primary
Candidates
Harry B. Hawes, member of the House of Representatives for Missouri's 11th district Willis Meredith, attorney Robert I. Young, farmer