Sir Peter Colleton, 2nd Baronet, FRS (17 September 1635 – 24 March 1694) was an English baronet of the Colleton Baronets and an MP.
He was the eldest son of Sir John Colleton, 1st Baronet, of Exeter, Devon, whom he succeeded in 1667.
He became a merchant and was a Member of the council of the Barbados in 1664–1684. He was a member of the Royal Adventurers into Africa in 1667–1672 and a member of the Hudson’s Bay Company from 1670 to his death.
He was elected a Fellow of the Royal Society in 1677.
He was MP for Bossiney (UK Parliament constituency) in 1681–1685 and 1689–1694.