The 2010 Cafés do Brasil Indy 300 was an IndyCar motor race held in front of approximately 14,000 people on October 2, 2010, at the Homestead–Miami Speedway in Homestead, Florida. It was the 17th and final showdown of the 2010 IndyCar Series, the final annual edition of the event in the IndyCar Series, and the 15th anniversary of the running of the race (including five years in the Championship Auto Racing Teams (CART) schedule). Chip Ganassi Racing driver Scott Dixon, who started from the second position, won the 200-lap race. Andretti Autosport's Danica Patrick finished second and her teammate Tony Kanaan took third.

Dixon's teammate Dario Franchitti won the pole position by posting the fastest two-lap effort in qualifying. He led the first 42 laps until Ryan Briscoe passed him on lap 43 but retook the position on the next lap. Franchitti led for a total of 128 laps, more than any other driver. He later opted to drive conservatively after his championship rival Will Power crashed in an unsuccessful attempt to lap Ryan Hunter-Reay on the 135th lap. Dixon took the lead on lap 152, and led a total of 47 laps en route to his third victory of the season — the 24th of his career. Patrick, one of five women drivers competing in the event, held off her teammate Kanaan in the final five laps to finish second by 0.0011 seconds.

2010 Cafés do Brasil Indy 300

There were five cautions and an event record-breaking 18 lead changes among seven drivers during the race. The result of the race won Franchitti the third Drivers' Championship of his career and the fourth for Chip Ganassi Racing from finishing eighth. Power's non-finish put him five points behind Franchitti in second place, while Dixon overtook Hélio Castroneves for third, and Briscoe finished the season in fifth place.

2010 Cafés do Brasil Indy 300

Background

The Cafés do Brasil Indy 300 was confirmed as part of the Indy Racing League's (IRL) 2010 schedule for the IndyCar Series in July 2009. It was the tenth consecutive year the race was held in the series, and the 15th running of the Cafés do Brasil Indy 300, counting the period from 1996 to 2000 when it was a Championship Auto Racing Teams (CART) event. The Cafés do Brasil Indy 300 was the 17th (and final) race scheduled for 2010 by the IRL, and was held on October 2, 2010, in Homestead, Florida, at Homestead–Miami Speedway. It was the second round held in Florida, following the Honda Grand Prix of St. Petersburg in March. Tire supplier Firestone brought three types of tire to the race: two dry compounds (black-sidewall "Primary" and red-banded "Alternate") and grooved rain tires.

2010 Cafés do Brasil Indy 300

At this late stage of the season, Team Penske driver Will Power was the points leader with 587 points, with Dario Franchitti 12 points behind in second. Hélio Castroneves was third with 501 points; Scott Dixon was fourth, and Ryan Briscoe was fifth. 53 points were available for the season's final round which meant Franchitti could win the championship. In the event the two drivers were tied on points, Power would be the champion having won five races to Franchitti's three. Franchitti needed to score 13 more points than Power to win the title.

After finishing third at the previous round in Motegi, Japan, Power said he was confident he could approach the final race more aggressively and believed it was the first time in his career he had the necessary equipment to win races, and was in a position to do so on oval tracks. Franchitti, who was familiar with Homestead-Miami Speedway, revealed he would not alter his plan and went to the track to win the race; he acknowledged that eliminating the 13-point deficit would not be easy. He also noted the high number of entries for the race had the potential to affect the championship battle, "I think the other guys on the track, they've got their own reasons. They're trying to win the race the same as any other race. And as long as I think they race with the same respect that they have all season, then I think we'll be OK. There's a couple of cars that I think really ... certainly one that's difficult enough to run a consistent lane. So I don't think you can expect much more."