Bunyoro sub-region is a region in Western Uganda that consists of the following districts:
Buliisa District
Hoima District
Kagadi District
Kakumiro District
Kibaale District
Kikuube District
Kiryandongo District
Masindi District
The area covered by the above districts is coterminous with the traditional Bunyoro Kingdom. Milton Obote abolished the traditional kingdoms in Uganda in 1967. When Yoweri Museveni re-established them in 1993, Bunyoro re-constituted itself.
The sub-region is home mainly to the Banyoro ethnic group. The people of Bunyoro are called Banyoro (singular: Munyoro). The Banyoro speak Runyoro, a Bantu language. Runyoro closely related to Rutooro, spoken by the people of the neighboring Toro sub-region. The language is often referred to as Runyoro/Rutooro.
According to the 2002 national census, the Bunyoro sub-region was home to an estimated 0.75 million people at that time.