The 2007–08 Premier Reserve League season is the ninth since its establishment. The events in the senior leagues during the 2006–07 season saw Watford, Charlton Athletic and Sheffield United all relegated and replaced by the promoted teams Birmingham City, Derby County and Sunderland.
Northern Champions Liverpool beat Southern Champions Aston Villa 3–0 in the Premier Reserve League Play-off Final and were crowned the National Champions.
Final league tables
Premier Reserve League North
Premier Reserve League South
Pld = Matches played; W = Matches won; D = Matches drawn; L = Matches lost; GD = Goal difference; Pts = PointsC = Champions
Play-off Final
Relegated and Promoted teams
These three teams were relegated from the Premier Reserve League at the end of this season: Derby County (South) Birmingham City (South) Reading (South) These three teams will promote to the Premier Reserve League at the start of next season: West Bromwich Albion (South) Stoke City (South) Hull City (North)