Chastain is a French surname. Notable people with the surname include:
Brandi Chastain (born 1968), American soccer player
David Chastain (born 1963), American guitarist
Don Chastain (1935–2002), American actor, singer and screenwriter
Elijah Webb Chastain (1813–1874), American politician, soldier and lawyer
James Garvin Chastain Sr., cofounder of the National Baptist Convention of Mexico Jane Chastain (born 1943), sports announcer and conservative political writer and commentator Jessica Chastain (born 1977), American actress and film producer Ken Chastain (born 1964), musician, engineer, and producer Michael Chastain (born 1955), blind athlete who played high school football in Troy, Michigan Nick Chastain (born 1981), American actor Ross Chastain (born 1992), American professional stock car racing driver Thomas Chastain (1921–1994), American author of crime fiction
Fictional characters
Misery Chastain, protagonist of fictitious romance novels in Stephen King's book Misery Darryl Louise (DL) Chastain, character in Thomas Pynchon's book Vineland.
French-language surnames
