Baylis is a surname. Notable people with the surname include:

Abraham B. Baylis (1811–1882), American businessman

Anna Baylis (born 1976), Australian mountain biker

Charles A. Baylis (1902–1975), American philosopher

Edward Baylis (1791–1861), British mathematician and businessman

Evan Baylis (born 1993), American football player

Francoise Baylis (born 1961), Canadian bioethicist

Frank Baylis (born 1962), Canadian politician

Geoff Baylis (1913–2003), New Zealand botanist

Gloria Baylis (1929–2017), Barbadian-Canadian civil rights activist

Hank Baylis (1923–1980), American baseball player

Henry Baylis (1826–1905), Australian police magistrate

James Baylis (died 1870), Irish theatre director

Jearld Baylis (born 1962), Canadian football player

John R. Baylis (1885–1963), American chemist and engineer

Keith Baylis (born 1947), English cricketer

Lilian Baylis (1874–1937), British theatrical producer and manager

Liz Baylis (born 1963), American sailor

Maggie Baylis (1912–1997), American graphic designer

Marc Baylis (born 1977), British actor

Matthew Baylis (born 1971), British novelist and screenwriter

Myrtle Baylis (1920–2014), Australian cricket and netball international

Nadine Baylis (1940–2017), British stage and costume designer

Thomas Baylis (disambiguation), several people

Trevor Baylis (1937–2018), English inventor

William Baylis (born 1962), American sailor

Baylis (surname)