Although hating his religion, his wife went to live with him, tolerating his infidelities while he refused to tolerate her religion. The unhappiness of this marriage was not due to Marguerite alone; the first trouble arose when she discovered his love for his mistress, Gabrielle d'Estrées, and, thinking herself equally privileged, she began to indulge in the same excesses. The result of so many annoyances and debaucheries, so much vexation, was an illness; as soon as she became convalescent, she returned to her mother at court where she speedily gained the ill will of the king by her profligate habits, her quarrels with both Catholics and Protestants, her intimacy with the Duke of Guise, her plottings with her younger brother, her cutting satires on court favorites.
She was sent back to Henry, upon the way meeting with the mishap of being insulted by archers and, with her maids, led away prisoner. Her husband was with difficulty persuaded to receive her, and, finding him all attentive to his mistress, Marguerite fled to Agen, where she made war upon him as a heretic; unable to hold her position there on account of her licentious manner of living and the exorbitant taxes imposed upon the inhabitants, she fled again and continued moving from one place to another, causing mischief everywhere, "consuming the remainder of her youth in adventures more worthy of a woman who had abandoned her husband than of a daughter of France." At last, she was seized and imprisoned in the fortress of Usson; here she was supported mainly by Elizabeth of Austria, widow of Charles IX.
When her husband became King of France, he refused to liberate her until she should renounce her rank; to this condition she refused to accede until after the death of her rival, the mistress of Henry--Gabrielle d'Estrées, Duchess de Beaufort. After the annulment of the marriage, Marguerite said: "If our household has been little noble and less bourgeois, our divorce was royal." She was permitted to retain the title of queen, her debts were paid and other great concessions granted. Her subsequent relations with Henry IV. were very cordial and fraternal; she even revealed political plots to him.
When, after nearly twenty years of captivity, Marguerite returned to Paris (1605), she gained the favor of everybody--the king, dauphin, and court ladies. She was present at the coronation of Marie de' Medici, and, by being tactful enough to keep apart from all intrigues, quarrels, and jealousies, she managed to win the good will of the king's favorites. She became the social leader, the queen inviting her to all court ceremonies and consulting her on all disputed questions of etiquette--even going so far as to intrust her with the reception of the Duke of Pastrana, who had come to ask the hand of Elizabeth of France. It is reported that in her last years she led a worse life than in her earlier days--she had become a woman of the bad world, resorting to every possible means to hide her age and to gain any vantage ground. In order to be well supplied with blond wigs, she kept fair-haired footmen who were shorn from time to time to furnish the supply. In the latter part of her life, spent at Paris and its vicinity, she fell a victim to hypochondria, suffering the most bitter pangs of remorse and terrible fear at approaching death. To alleviate this, she founded a convent where she taught the children music. She died in 1615, in Paris, "in that blended piety and coquetry which formed the basis of a character unable to give up gallantries and love."