The 2017–18 USC Trojans women's basketball team represents the University of Southern California during the 2017–18 NCAA Division I women's basketball season. The Trojans, led by first year head coach, 6th overall Mark Trakh, play their home games at the Galen Center and were members of the Pac-12 Conference. They finished the season 20–11, 9–9 in Pac-12 play to finish in seventh place. They defeated Washington State in the first round before losing to Stanford in the quarterfinals of the Pac-12 women's basketball tournament to Stanford. They would have clinched the automatic berth to the 2018 Women's National Invitation Tournament, but declined to participate, despite being the highest-ranked non-NCAA team in the Pac-12.
Previous season
They finished the season 14–16, 5–13 in Pac-12 play to finish in a 4-way tie for ninth place. They lost in the first round Pac-12 women's basketball tournament to California. After that game, Coach Cynthia Cooper-Dyke resigned.